Tupelo is a city in and the county seat of Lee County, Mississippi, United States. Founded in 1860, the population was 37,923 at the 2020 census. It is the seventh-most populous city in Mississippi and is considered a commercial, industrial, and cultural hub of northern Mississippi.
Southeast
Tupelo
Lee County, MS
Population
37,939
Walk Score
61 · Somewhat Walkable
Median rent
$922
Median home value
$184,100
Founded
1860
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On the National Register
Historic districts
- Downtown Tupelo Historic District · listed 2014
- Downtown Tupelo Historic District (Boundary Increase) · listed 2025
- Highland Circle Historic District · listed 2006
- Mill Village Historic District · listed 1992
- North Broadway Historic District · listed 1985
- South Church Street Historic District · listed 1992
- Tombigbee State Park · listed 1999
- Tupelo Downtown Neighborhood Historic District · listed 2021
- Tupelo Homesteads · listed 1997
Notable landmarks
- Carnation Milk Plant · listed 2009
- Chokkilissa’-Old Town
- Clark, R.C., House · listed 2010
- First Methodist Church · listed 1990
- Goodlett, R. F., House · listed 1992
- Lee County Courthouse · listed 1992
- Mutt-Thomason Site · listed 1978
- North Church Primary School · listed 1992
- Old Superintendent's House, Tupelo Fish Hatchery · listed 1992
- Peoples Bank and Trust Company · listed 1978
- Spain House · listed 2011
- Spight, F. L., House · listed 1992
- Spring Hill Missionary Baptist Church
- Spring Hill Missionary Baptist Church · listed 2023
- Stewart-Anderson House · listed 1994
- Tupelo National Battlefield · listed 1966
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